A management Technique for Protein Version Information based on Local Sequence Alignment and Trigger 


Vol. 12,  No. 1, pp. 51-62, Feb.  2005
10.3745/KIPSTD.2005.12.1.51


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  Abstract

After figuring out the function of an amino acid sequence, we can infer the function of the other amino acids that have similar sequence composition. Besides, it is possible that we alter protein whose function we know, into useful protein using genetic engineering method. In this process, an original protein amino sequence produces various protein sequences that have different sequence composition. Here, a systematic technique is needed to manage protein version sequences and reference data of those sequences.Thus, in this paper we proposed a technique of managing protein version sequences based on local sequence alignment and a technique of managing protein historical reference data using Trigger. This method automatically determines the similarity between an original sequence and each version sequence while the protein version sequences are stored into database. When this technique is employed, the storage space that stores protein sequences is also reduced. After storing the historical information of protein and analyzing the change of protein sequence, we expect that a new useful protein and drug are able to be discovered based on analysis of version sequence.

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[IEEE Style]

K. S. Jung, S. H. Park, K. H. Ryu, "A management Technique for Protein Version Information based on Local Sequence Alignment and Trigger," The KIPS Transactions:PartD, vol. 12, no. 1, pp. 51-62, 2005. DOI: 10.3745/KIPSTD.2005.12.1.51.

[ACM Style]

Kwang Su Jung, Sung Hee Park, and Keun Ho Ryu. 2005. A management Technique for Protein Version Information based on Local Sequence Alignment and Trigger. The KIPS Transactions:PartD, 12, 1, (2005), 51-62. DOI: 10.3745/KIPSTD.2005.12.1.51.

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